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Nicotinamide Adenine Dinucleotide (NAD+) is an essential molecule found in every cell of your body.













What is NAD?-

Nicotinamide Adenine Dinucleotide (NAD) is a metabolic co-enzyme that structures, repairs, and is an essential component of energy production (mitochondrial function); heavily involved in DNA repair and cell repair; responsible for turning certain genes on and off; and essential for maintaining neurotransmitter levels, for the proper functioning of the brain.

These specialized enzymes require constant replenishment.

Below are some instances in which the body can lose or degrade natural NAD levels:

  • Substance abuse

  • Alcoholism

  • Post Traumatic Stress

  • Anxiety

  • Depression

  • Chronic Traumatic Encephalopathy (CTE)*

  • Alzheimer's

  • Parkinson's

  • Neurodegenerative Diseases

  • Natural aging process



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What is NAD+ Therapy?

High dose intravenous infusions of pure NAD+ bypasses the digestive system and delivered straight to the cells for better absorption. NAD+ works rapidly to repair cells throughout the body and neurons in the brain.

NAD+ is a coenzyme of Vitamin B3 (niacin), which means it’s a small helper molecule that binds to a protein molecule in order to activate an enzyme. Enzymes are responsible for over 5,000 different biochemical reactions throughout the body and NAD+participates in more reactions than any other vitamin-derived molecule.

When your NAD+ levels are increased, your cells produce more energy, your good genes are “turned on”, DNA is repaired, and many other functions are optimized. Since NAD+ is such a powerful and prolific molecule in the body, high dose IV therapy can be helpful for many different conditions including: substance abuse,addiction,alcoholism, anxiety, stress, depression, PTSD, chronic fatigue, chronic pain, brain injury, mitochondrial disease and neurodegeneration.



* Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease of the brain found in athletes and others with a history of repetitive brain trauma, including concussions and even sub-concussive hits to the head. This disease was previously called dementia pugilistica (DP), or “punch-drunk,” as it was initially found in those with a history of boxing. CTE is now most commonly found in professional athletes participating in football, ice hockey, professional wrestling, stunt performing, bull riding, rodeo, and other contact sports resulting in repetitive brain trauma.

In 2015, researchers from the Department of Veterans Affairs and Boston University announced that they had identified CTE in 96 percent of the 91 deceased NFL players they had examined and in 79 percent of all football players. CTE often results in symptoms of dementia, such as memory loss, aggression, confusion and depression, which may appear years—or even decades—after the trauma. -

Nad+ what is it? Hear it from Charles Brenner the bio chemist who discovered Nicatinamide Riboside NR

What is NAD- Dr Brenner -
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In this in-depth radio interview, Dr Brenner, bio chemist, explains the significance of NAD and why he believes supplementation with NR could help us “age better.” He also elaborates on why he refuses to describe NR as “miraculous or magic” and explains why he is uncomfortable with the often-heard expression, ‘anti-aging,’ in the marketing of human longevity.



WHAT IS NAD? (nicatinamide adenine dinnucleotide)


Nad is the central regulator of metabolism. In every cell, in every tissue, metabolism is the sum total of the prosesis that convert our food, our protein,fat and carbohydrate into energy (ATP) that converts our building blocks into novel proteins into hormones, lipids, new cells, DNA, RNA protein.

Metabolism is required for every organ system to function, for the kidney to work, for the heart to beat, for the brain to have an idea, for the peripheral nerves to fell, for the skeletal muscles to flex. NAD is the component of every cell.

Metabolism declines in ageing and is also disregulated by a number of stress conditions. Both ageing and stress conditions depress metabolism and thats where we think the value of restoring and boosting NAD is.

WHAT IS NAD+?  What is the +?

There are 4 forms NAD coenzymes. Coenzyme refers to a molecule that is not consumed in the process of it performing it's biological function., NAD+ cycles back and forth to NADH in the course of oxidizing fuels. NAD+ is converted to NADH, NADH is reoxidised in 80+ to make energy (ATP).


There are a number of conditions of metabolic stress including DNA damage. time zone disruption (ie jetlag, night shift) oxidative stress, sunlight damage, over eating, over nutrition, alcohol exposure that lead to a declining NAD. Then there is disease protesis like heart failure, and neurodegeneration that attack NAD. Boosting NAD is a reasonable goal, just as people want to remain fit and active and try to retain optimum organ function and vitality. Boosting NAD is one of the keys to ageing better- NR boosts NAD in times of cellular stress.  

Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.




The study of the genetic basis of aging is still in its infancy, and the heady excitement of new discoveries being made in laboratories around the world is tempered by the considerable confusion about how to interpret them. It's a great time to be a molecular biologist with the spirit of adventure and a taste for controversy. Biochemistry and genetics are complicated subjects, and it can take the patience of a saint, as well as formidable scientific skills, to unravel the molecular threads that make up the exquisite tapestry of life.

It always helps, of course, when one particular thread in the tapestry appears again and again, like a leitmotif in a Wagner opera, to link seemingly disparate elements of the picture, thus helping to make it a bit clearer. It's especially helpful if such a thread appears not just in different parts of the picture of a given organism, but in those of many different organisms, from the simplest to the most complex.


Together, they make up the Big Picture. DOWNLOAD FULL COPY